Gifty Assifuah got her brace in the game in added time of the first half to make it three goals for the Black Queens.
The win has boosted the morale of the Black Queens as they prepare to take on Senegal in the return leg on Tuesday, April 11.
The Black Queens previously walloped Benin 3-0 in February in an international friendly and had their next match against Togo canceled.
Coach Nora Hauptle is building a formidable team to compete for the West Africa Football Union (WAFU) Cup of Nations and the African Women's Cup of Nations qualifiers (WAFCON).