Dr Cryme is the stage name of Darlington Kwasi Agyekum, a Ghanaian rapper and early proponent of the Ghanaian "twipop" genre. Dr. Cryme has also performed as a TV presenter, a brand ambassador, and is CEO of Twipop Recordz.

Agyekum was born in Tema and began making music in his early school days. He studied at the Datus School and then attended ASUTECH in Cape Coast and Sotech in Somanya before earning a certificate in broadcast journalism from the Ghana Institute of Journalism.

Agyekum's stage name Dr. Cryme is an acronym that means Doctor (of the) Creative Rhymes You Most Enjoy. Whilst in high school, Agyekum gained himself underground popularity through "Kasahare Level"; a popular rap competition on Adom FM (an Accra-based radio station) which featured Sarkodie, Stay Jay, and the like.

It was through these rap battles and his style of music which caught the eye of the Ejams record label to sign him in 2010. He released his first hit single "Kill me shy" the same year. In 2011, he released his debut album called "Finally Finally". In 2012, his "Kill me shy" emerged the song "Hiplife song of the year" at the Ghana Music Awards.

He was also nominated for the "Song Writer of the year", "Most Popular Song of the Year", and "Hiplife/Hip Hop Artiste of the Year" categories. Agyekum released his sophomore album entitled Showtime in February 2018. The twenty-tracked album includes the hit single "Koko Sakora" which features Sarkodie.

Dr. Cryme performed as a presenter for 4 Syte TV in 2011. He hosted the ‘Top 10 Videos’ which was aired on ETV Ghana. In the same year, Agyekum was officially unveiled as the Brand Ambassador for Samsung Ghana.

Agyekum was involved in the UN Volunteers Day Chokor project which was pegged to the Copenhagen conference.

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